Natural matrices such as type 1 collagen and Matrigel are widely used in 3D bioprinting, but their scalability for high-throughput spheroid studies remains uncertain. Using CELLCYTE X live-cell imaging, breast cancer cells embedded in TeloCol®-10 collagen were monitored for spheroid formation and migration. Compared to Matrigel, TeloCol®-10 provided higher stability over longer incubation times, avoiding detachment and degradation during media exchange.
Learn more about how:
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CELLCYTE X enables real-time monitoring of 3D spheroid models
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Collagen and Matrigel differ in supporting spheroid stability and migration
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TeloCol®-10 improves reproducibility for long-term, high-throughput studies
